NFL injury report: Updates on Alvin Kamara, Christian McCaffrey and more for Week 4

The NFL injury report is always filled with some of the game’s best stars, leaving fans and fantasy football managers scrambling to find out who will play. Heading into Week 4 of the 2022 NFL season, Dallas Cowboys star QB Dak Prescott is already inching toward a return from thumb surgery.

Bookmark this page for daily injury updates and news on NFL stars from across the league, whether they will play in Week 4 and how their injuries impact fantasy football.

Here is the latest injury news for some of the NFL’s biggest stars and the impact it will have on Week 4 in Sportsnaut’s NFL injury report.

Related: NFL Week 4 power rankings

Tua Tagovailoa, quarterback, Miami Dolphins

NFL: Buffalo Bills at Miami Dolphins
Rich Storry-USA TODAY Sports

Miami Dolphins quarterback Tua Tagovailoa left Thursday’s game with a head injury after his head slammed into the ground, causing a fencing reaction. He was taken off the field on a stretcher and hospitalized, undergoing a series of tests during the night.

Tagovailoa, who seemed to first suffer a head injury against Buffalo, is now being evaluated back in Miami for a neck injury that occurred against Cincinnati, and now he will go through the NFL concussion protocol. While the Dolphins have 10 days until their next game, the scrutiny surrounding Tagovailoa seemingly playing through a concussion in Week 3 and then suffering a traumatic head injury on Thursday Night Football suggests Miami will be more cautious this time around. Consider him unlikely to play in Week 5.

Alvin Kamara, running back, New Orleans Saints

Listed as questionable on the NFL Injury report for Week 4, running back Alvin Kamara is among the New Orleans Saints inactives on Sunday morning. It comes as a bit of a surprise, because the rib injury didn’t seem to be a long-term issue that would sideline him for multiple games. With the All-Pro offensive weapon unavailable, Mark Ingram slides in as the starting running back. Fantasy managers should view Ingram as a mid-tier RB2 for Week 4.

Christian McCaffrey, running back, Carolina Panthers

NFL: Cleveland Browns at Carolina Panthers
Jim Dedmon-USA TODAY Sports

Stop me if you’ve heard this one before. Carolina Panthers running back Christian McCaffrey is on the injury report and is considered questionable for Sunday’s matchup against the Cardinals. Unfortunately, this isn’t some sick joke. CMC really is dealing with a quad injury and had to miss practice on Wednesday and Thursday.

Coach Matt Rhule indicated that the injury happened after their Week 3 win, but Ian Rapoport suggests there’s “optimism” that McCaffrey should be good to go on game day. Following a limited participation in practice on Friday, McCaffrey is designated as questionable to play on the final Week 4 NFL injury report. While he is expected to play, fantasy managers should prepare alternatives just in case he isn’t able to suit up.

D’Andre Swift, running back, Detroit Lions

nfl injury report: d'andre swift

One of the game’s most-explosive running backs, Swift suffered a shoulder sprain in last week’s loss to the Minnesota Vikings. He’s now expected to miss multiple weeks of action. This is not great news for Jared Goff and the Lions’ offense heading into a Week 4 outing against the lowly Seattle Seahawks.

  • D’Andre Swift stats (2022): 231 rushing yards, 8 catches, 77 yards, 8.8 yards per touch, 2 TD

With Swift sidelined, Jamaal Williams will continue to get the bulk of the touches for Detroit out of the backfield. He’s put up 197 total yards and four touchdowns in three games. Taking on a Seahawks defense that has allowed the sixth-most fantasy points to running backs, Williams becomes a solid streaming option.

Related: Sportsnaut’s Week 4 NFL defensive rankings

Mac Jones, quarterback, New England Patriots

nfl injury report: mac jones

Mac Jones — who is dealing with a high ankle sprain — has officially been ruled out for the team’s game against the Packers on Sunday afternoon. After reports claimed that Jones would be a game-time decision, and he even showed up at practice on Friday, there was nothing real to the hope, and the team’s starter will be out for at least one game starting this week.

Brian Hoyer will now be under center for Green Bay in Week 4. The Green Bay Packers pass rush will likely cause fits for the Patriots’ offensive line, and the Pack’s secondary matches up well against a below-average receiving corps. Perhaps, running back Rhamondre Stevenson could be a nice buy-low option with the run game expected to be a bigger focal point. The second-year talent from Oklahoma put up 101 total yards and a touchdown on 17 touches in last week’s loss to the Baltimore Ravens.

Zach Wilson, quarterback, New York Jets

nfl injury report: zach wilson
Danielle Parhizkaran/ / USA TODAY NETWORK

Finally, some good news on our NFL injury report. After missing the first three games of the season with a knee injury, Zach Wilson is ready to return to action. Jets head coach Robert Saleh said he has been fully cleared and will play this week against the Pittsburgh Steelers.

With Wilson sidelined through the first three games, Joe Flacco has thrown for 901 yards with five touchdowns and three interceptions. His top target has been stud rookie Garrett Wilson (18 catches, 214 yards). We’ll see if Wilson has the same chemistry with his receivers.

Related: Sportsnaut’s NFL Week 4 power rankings

Jameis Winston, quarterback, New Orleans Saints

Dealing with multiple fractures in his back, Jameis Winston still suited up for last week’s contest against the Carolina Panthers, but he didn’t have much success. While Winston has always been a bit erratic, coach Dennis Allen says the team has no plans to change quarterbacks.

Winston hasn’t practiced with the team at all this week as they prepare for an early Sunday showdown in London against the Vikings. New Orleans now has ruled out Winston for Sunday’s tilt. In his absence, quarterback Andy Dalton steps back into a starting role on a temporary basis but isn’t worth any looks in fantasy football.

Related: 5 key players to watch in Minnesota Vikings vs New Orleans Saints showdown in London

Michael Thomas, wide receiver, New Orleans Saints

Just when Michael Thomas finally returned to the field and was looking healthy, the All-Pro wideout suffers a toe injury. He had to leave the Week 3 loss to Carolina, though Ian Rapoport has suggested the injury “isn’t believed to be serious.” Serious or not, the Saints’ top target was ruled out on Friday with nearly 48 hours until kickoff for Sunday’s game. With Thomas out, rookie Chris Olave will continue being a target magnet in the Big Easy.

Dalvin Cook, running back, Minnesota Vikings

NFL: Detroit Lions at Minnesota Vikings
Jeffrey Becker-USA TODAY Sports

Cook exited Sunday’s win over the Detroit Lions in the third quarter after dislocating his shoulder for the second time in his NFL career and was almost immediately ruled out for the duration.

Cook surprisingly took the field for a full practice on Thursday and was a full participant in practice on Friday. Minnesota is so confident in him being ready for the Week 4 matchup that it removed him from the NFL injury report. For those who added Alexander Mattison, leave him on the bench against the Saints.

David Montgomery, running back, Chicago Bears

Coming off a 122-yard effort, David Montgomery had to leave early in Week 3 with injuries to his ankle and knee. Despite being labeled as day-to-day, now the Bears starting running back has been ruled out for Sunday’s matchup.

Second-year-pro Khalil Herbert was incredible as a fill-in, racking up a career-high 157 rushing yards and two touchdowns on 20 carries against Houston. Chicago’s next opponent is the New York Giants, and they’ve allowed the seventh-most rushing yards through Week 3, meaning if Herbert’s still available in your fantasy leagues, he’s worth a start.

Amon-Ra St. Brown, wide receiver, Detroit Lions

nfl injury report: amon-ra st. brown
Jeffrey Becker-USA TODAY Sports

Our Week 4 NFL injury report is something to pay attention to from a fantasy perspective. That’s especially true with this productive young wide receiver limited by an ankle injury last Sunday. Reports indicate that St. Brown’s injury is not expected to be long-term.

  • Amon-Ra St. Brown stats (2022): 23 receptions, 253 yards, 3 TD, 69.7% catch rate

However, St. Brown is among the Week 4 NFL inactives after Detroit ruled him out on the NFL injury report released on Friday. In St. Brown’s absence, Josh Reynolds becomes a strong FLEX play and climbed up our Week 4 fantasy wide receiver rankings.

Hunter Renfrow, wide receiver, Las Vegas Raiders

After suffering a concussion on the final play of their Week 2 overtime loss, Hunter Renfrow missed Las Vegas’ Week 3 loss to the Tennessee Titans. Unfortunately, he hasn’t been able to practice since. Renfrow will not be able to go this coming Sunday against the Denver Broncos.

With his top slot guy sidelined last Sunday, Derek Carr completed 26-of-44 passes for 303 yards with two touchdowns and one interception. Mack Hollins put up a career-best eight-catch, 158-yard outing while tying Davante Adams for the team lead in targets with 10. Regardless of Renfrow’s status in our NFL injury report moving forward, Hollins is a waiver option in fantasy football.

Related: NFL Week 4 fantasy football rankings

Michael Gallup, wide receiver, Dallas Cowboys

NFL injury report: Michael Gallup
im Heitman-USA TODAY Sports

Michael Gallup missed the first two contests of the season as he works his way back from a torn ACL he suffered late last season. Gallup was in line to make his season debut last week against the New York Giants. But the Cowboys decided to hold him out.

Gallup will be in the lineup for the Cowboys this week. Though, he’s almost certainly going to be on a pitch count. In DFS leagues, former seventh-round pick Noah Brown from Ohio State has become a decent flex option. He’s recorded five catches in each of the first two games of the season. In the two outings Cooper Rush has started for the injured Dak Prescott, Brown has caught 10-of-12 targets for 145 yards and a touchdown.

Related: Ranking NFL offenses heading into Week 4

Keenan Allen, wide receiver, Los Angeles Chargers

nfl injury report: keenan allen
Kirby Lee-USA TODAY Sports

Allen suffered a hamstring injury in the opener against the division-rival Las Vegas Raiders in Week 1. The star wide receiver has missed the two games since with Los Angeles dropping both affairs. Now he’s set to miss a third, as he won’t play in Week 4 either.

Obviously, this isn’t the news Chargers quarterback Justin Herbert wanted to hear. He’s lacked consistent weapons in the passing game with Allen sidelined. That included high-priced wide receiver Mike Williams hauling in just 1-of-6 targets for 15 yards in Los Angeles’ ugly Week 3 loss to the Jacksonville Jaguars.

Julio Jones, wide receiver, Tampa Bay Buccaneers

NFL: Tampa Bay Buccaneers at Dallas Cowboys
Tim Heitman-USA TODAY Sports

Here we go again. Tom Brady‘s newest go-to option could be looking at missing more time after a strong debut with the Buccaneers. After being unable to suit up in Week 2 against New Orleans, Jones was quickly ruled out once again in Week 3 as he works his way back from a knee injury. Coach Todd Bowles has Jones as a game-time decision for Sunday as he recovers from a partially torn PCL.

The seven-time Pro Bowl receiver was clocked as the seventh-faster ballcarrier in Week 1, so prior to the knee ailment he’s dealing with, Jones had been feeling pretty good. The better news for a struggling Brady will be if Jones is ready to return Week 4 against the Kansas City Chiefs. Tom Terrific will need that.

Chris Godwin, wide receiver, Tampa Bay Buccaneers

Able to go Week 1 after suffering a torn ACL last season, Godwin went down with a strained hamstring in Tampa Bay’s season opener. Initially, the expectation was that Godwin would miss some time. He’s now been sidelined for the past two weeks.

Godwin was able to get in a limited practice session on Friday after sitting out the day before, but being that he’s coming back from a hamstring issue, it’s possible he misses this week’s outing against the Chiefs. Expect Mike Evans (return from suspension) and the aforementioned Julio Jones (if active) to see a large target share come Sunday night.

Related: Young fantasy football stars to target in 2022

Dalton Schultz, tight end, Dallas Cowboys

A surprise addition to the Week 3 NFL injury report, Schultz is dealing with a PCL sprain to his right knee. He missed Dallas’ Week 3 win over the New York Giants. With Schultz able to get back-to-back limited practices in, the Cowboys’ starting tight end is expected to play on Sunday, according to Ian Rapoport. Young tight ends Peyton Hendershot and Jake Ferguson are not fantasy-relevant options with Schultz questionable to go.

Dak Prescott, quarterback, Dallas Cowboys

nfl injury report: dak prescott
Kevin Jairaj-USA TODAY Sports

Dak Prescott has missed each of the past two games after undergoing surgery on his throwing hand. It looks like he is still at least a week away from returning, according to Cowboys owner Jerry Jones. In his stead, Cooper Rush has played at a high level.

  • Cooper Rush stats (2022): 63% completion, 514 yards, 2 TD, 0 INT, 91.7 QB rating

With Prescott ruled out for Week 4 as he targets a Week 6 return, Rush becomes an under-the-radar DFS play. As noted above, Noah Brown also becomes an option, given how he’s connected with Rush over the past couple weeks.

NFL injury report: Players likely inactive for Week 4

NFL injury report: Players expected to play in Week 4

  • Joe Mixon, running back, Cincinnati Bengals
  • Rondale Moore, wide receiver, Arizona Cardinals
  • Michael Thomas, wide receiver, New Orleans Saints
  • Jarvis Landry, wide receiver, New Orleans Saints
  • Jaylen Waddle, wide receiver, Miami Dolphins
  • Stefon Diggs, wide receiver, Buffalo Bills

This article was originally published on and is republished here with permission.

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